In this talk Sigurður Rúnar Guðmundsson will present the work I was involved in during my PhD with emphasis on correlative light and electron microscopy (CLEM) analysis of phagophores and autophagosomes of both selective and un-selective autophagy 

Classical scrapie is a contagious, fatal neurodegenerative disease that affects sheep. It has been endemic in Iceland for about 140 years.

The SARS-CoV-2 virus causing COVID-19 was first identified at the end of 2019 and has as of now by 16th of January 2021 caused close to 95 million cases and over 2 million deaths.

Polysaccharide-protein conjugates have been developed to overcome the T-independent response, hyporesponsiveness to repeated vaccination, and poor immunogenicity in infants of polysaccharides.

Microglia, the brain-resident immune cells, are critically involved in many physiological and pathological processes, including neurodegeneration.

In this seminar, Berglind Eva Benediktsdóttir will take you through the world of EVs as they relate to drug delivery and isolation strategies, then zoom in on the current status of EV isolation from the above-mentioned cell lines using SEC and centrifugal filtration, and how Jess (capillary western blotting) has helped in confirming the isolation of EVs.

Adrián López García de Lomana will present ongoing efforts towards the inference of a gene regulatory network model for endothelium function from all publicly available bulk and single-cell expression data sets, including EndoDB that contains up to 4,741 bulk and 5,847 single cell endothelial transcriptomes.

In this talk, Hildur Knútsdóttir will explain how we exploit this heterogeneity in 3D organoid models of invasion to identify novel drivers of metastasis

In this talk Linda Viðarsdóttir, will explain the function of the lncRNA PTENpg1 asRNA and its part in vemurafenib resistance and how it could be an attractive therapeutic target.

A broad range of diseases are identified based on histology. Today, most pathological tissue samples are stored as formalin-fixed paraffin embedded (FFPE) tissue blocks, which is the gold standard for histopathological analysis.